Perspectives on Structural Molecular Biology Visualization: From Past to Present

J Mol Biol. 2018 Oct 19;430(21):3997-4012. doi: 10.1016/j.jmb.2018.07.009. Epub 2018 Jul 23.


Visualization has been a key technology in the progress of structural molecular biology for as long as the field has existed. This perspective describes the nature of the visualization process in structural studies, how it has evolved over the years, and its relationship to the changes in technology that have supported and driven it. It focuses on how technical advances have changed the way we look at and interact with molecular structure, and how structural biology has fostered and challenged that technology.

Keywords: molecular graphics; molecular modeling; structural molecular biology; visualization.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Humans
  • Models, Molecular*
  • Molecular Conformation
  • Molecular Structure*
  • Protein Conformation
  • Proteins / chemistry
  • Software*


  • Proteins