Cellular Dynamics Driving Elongation of the Gut

Kaelyn Sumigray; Terry Lechler

doi:10.1016/j.devcel.2018.06.027

Cellular Dynamics Driving Elongation of the Gut

Dev Cell. 2018 Jul 16;46(2):127-128. doi: 10.1016/j.devcel.2018.06.027.

Authors

Kaelyn Sumigray¹, Terry Lechler²

Affiliations

¹ Departments of Dermatology and Cell Biology, Duke University Medical Center, Durham, NC, USA.
² Departments of Dermatology and Cell Biology, Duke University Medical Center, Durham, NC, USA. Electronic address: terry.lechler@duke.edu.

PMID: 30016614
DOI: 10.1016/j.devcel.2018.06.027

Abstract

During embryonic development, the midgut needs to undergo extensive elongation to form the small intestine. In this issue of Development Cell, Wang et. al. (2018) explore the cell dynamics of this tissue and find that regulated re-integration of cells into the epithelial layer is important for elongation.

Publication types

Comment

MeSH terms

Digestive System*
Endoderm*
Epithelial Cells
Female
Humans
Pregnancy

Grants and funding

R01 DK117981/DK/NIDDK NIH HHS/United States