Type 2 Choroidal Neovascularization in a Choroidal Granuloma Detected Using Swept-Source Optical Coherence Tomography Angiography

Ophthalmic Surg Lasers Imaging Retina. 2018 Jul 1;49(7):534-539. doi: 10.3928/23258160-20180628-11.

Abstract

The authors describe the imaging characteristics and progression of a type 2 choroidal neovascular membrane (CNV) using swept-source optical coherence tomography (SS-OCTA). A 27-year-old male presented with an active possible tubercular choroidal granuloma associated with exudative retinal detachment in the right eye. The patient received anti-tubercular drugs, oral corticosteroids, and intravitreal bevacizumab and showed complete resolution in 3 months. At the 7-month follow-up, SS-OCTA imaging revealed a type 2 CNV. SS-OCTA is a very useful tool to detect and monitor the growth of CNV in active and healed posterior uveitis without the risks of dye-based angiography. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:534-539.].

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Angiogenesis Inhibitors / therapeutic use
  • Antitubercular Agents / therapeutic use
  • Bevacizumab / therapeutic use
  • Choroid Diseases / complications*
  • Choroid Diseases / diagnosis
  • Choroid Diseases / drug therapy
  • Choroidal Neovascularization / diagnostic imaging*
  • Choroidal Neovascularization / drug therapy
  • Choroidal Neovascularization / etiology
  • Coloring Agents / administration & dosage
  • Fluorescein Angiography
  • Granuloma / complications*
  • Granuloma / diagnosis
  • Granuloma / drug therapy
  • Humans
  • Indocyanine Green / administration & dosage
  • Interferon-gamma Release Tests / methods
  • Intravitreal Injections
  • Male
  • Retrospective Studies
  • Tomography, Optical Coherence / methods*
  • Tuberculosis, Ocular / complications*
  • Tuberculosis, Ocular / diagnosis
  • Tuberculosis, Ocular / drug therapy
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors

Substances

  • Angiogenesis Inhibitors
  • Antitubercular Agents
  • Coloring Agents
  • VEGFA protein, human
  • Vascular Endothelial Growth Factor A
  • Bevacizumab
  • Indocyanine Green