Tenosynovial Giant Cell Tumor of the Clinoid: Rare Condition

Aaron Gelinne; Erinc Akture; Bruce Tranmer

doi:10.1016/j.wneu.2018.07.066

Tenosynovial Giant Cell Tumor of the Clinoid: Rare Condition

World Neurosurg. 2018 Oct:118:168-171. doi: 10.1016/j.wneu.2018.07.066. Epub 2018 Jul 17.

Authors

Aaron Gelinne¹, Erinc Akture², Bruce Tranmer²

Affiliations

¹ Department of Neurological Surgery, University of Vermont Medical Center, Burlington, Vermont, USA. Electronic address: agelinne@med.uvm.edu.
² Department of Neurological Surgery, University of Vermont Medical Center, Burlington, Vermont, USA.

PMID: 30026165
DOI: 10.1016/j.wneu.2018.07.066

Abstract

Background: A tenosynovial giant cell tumor (TGCT) is a rare type of tumor that primarily arises from the tendon sheath, synovium, and bursae. In rare cases, these tumors can affect joints of the head and neck such as the temporomandibular joint. This is the only case to our knowledge of an intracranial TGCT tumor of the clinoid.

Case description: We present the case of a 25-year-old female with a 2-year history of progressively blurred vision in her left eye without visual field defects. She denied any headaches or symptoms referable to the left eye region. Past medical history was significant for meningitis at 10 months of age. Family history was noncontributory with no history of brain tumors.

Conclusions: A tumor originating from the left anterior clinoid was found intraoperatively and confirmed by histology to be a TGCT.

Keywords: Clinoid; Giant cell; Intracranial; Soft tissue; Tumor.

Publication types

Case Reports

MeSH terms

Adult
Brain Neoplasms / diagnosis
Brain Neoplasms / surgery*
Diagnosis, Differential
Female
Giant Cell Tumor of Tendon Sheath / diagnosis
Giant Cell Tumor of Tendon Sheath / surgery*
Giant Cell Tumors / diagnosis
Giant Cell Tumors / surgery*
Humans
Neck / pathology
Neck / surgery
Rare Diseases / diagnosis
Temporomandibular Joint / surgery*