Lipoma removal using a high-frequency ultrasound-guided injection of a Class III CE-marked device-Empirical findings

J Cosmet Dermatol. 2019 Apr;18(2):469-473. doi: 10.1111/jocd.12681. Epub 2018 Jul 19.

Abstract

Background: Lipomas are very common benign neoplasms, which constitute 99% of all adipose-derived tumors. Main treatment option includes surgical excision, which is unacceptable for a number of patients seeking ways to improve esthetic appearance of their skin. Therefore, alternative treatment options are being sought.

Objective: The aim of the present study was to assess the efficacy of lipoma removal using a Class III CE-marked device (Aqualyx™) administered as a high-frequency ultrasound-guided injection (intralipotherapy).

Methods: A total of 17 lipomas were treated. The procedure involved a high-frequency ultrasound-guided injection. A maximum of 3 injections per a lipoma were performed. High-frequency ultrasound was used for assessing the size of lipomas and monitoring treatment-induced changes to the lipomas and adjacent tissue.

Results: Response to treatment was achieved in all cases. A complete removal was achieved in 70.59% of lipomas. The remaining 29.41% of lipomas were not completely removed, yet significantly reduced in size.

Conclusion: An injection of Aqualyx™, a CE-marked drug, is a good noninvasive treatment of lipomas. Ultrasound guided procedure is recommended, as it ensures appropriate technique and enables monitoring treatment-induced changes. Considering a low number of published reports of such treatment, it is crucial to continue this research.

Keywords: high-frequency ultrasound; injection lipolysis; intralipotherapy; lipoma; sodium deoxycholate.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Cosmetic Techniques / instrumentation*
  • Female
  • Galactans / administration & dosage*
  • Humans
  • Injections, Intradermal / methods
  • Lipoma / diagnostic imaging
  • Lipoma / therapy*
  • Middle Aged
  • Skin Neoplasms / therapy*
  • Treatment Outcome
  • Ultrasonography, Interventional

Substances

  • Aqualyx
  • Galactans