Spoon-Feeding Ribosomes to Autophagy

Mol Cell. 2018 Jul 19;71(2):197-199. doi: 10.1016/j.molcel.2018.07.003.

Abstract

The ribosome, a ribonucleoprotein machine for protein synthesis, can also serve as an abundant nutrient source under starvation conditions. In a recent issue of Science, Wyant et al. (2018) discovered a specialized "spoon" to "scoop up" more ribosomes for degradation by autophagy.

Publication types

  • Comment

MeSH terms

  • Autophagy
  • Humans
  • Receptors, Cytoplasmic and Nuclear*
  • Ribosomes
  • Starvation*

Substances

  • Receptors, Cytoplasmic and Nuclear
  • ribosome receptor