Trafficking of Lysosomal Enzymes in Normal and Disease States

J Clin Invest. 1986 Jan;77(1):1-6. doi: 10.1172/JCI112262.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biological Transport, Active
  • Endoplasmic Reticulum / enzymology
  • Endoplasmic Reticulum / metabolism
  • Enzyme Precursors / biosynthesis
  • Glycogen Storage Disease / enzymology*
  • Glycogen Storage Disease / genetics
  • Glycogen Storage Disease / metabolism
  • Golgi Apparatus / metabolism
  • Histocytochemistry
  • Humans
  • Lectins, C-Type*
  • Lysosomes / enzymology*
  • Lysosomes / metabolism
  • Mannose-Binding Lectins*
  • Mannosephosphates / metabolism
  • Oligosaccharides / metabolism
  • Phosphotransferases / deficiency
  • Protein Processing, Post-Translational
  • Receptors, Cell Surface*
  • Receptors, Immunologic / analysis

Substances

  • Enzyme Precursors
  • Lectins, C-Type
  • Mannose-Binding Lectins
  • Mannosephosphates
  • Oligosaccharides
  • Receptors, Cell Surface
  • Receptors, Immunologic
  • mannose receptor
  • mannose-6-phosphate
  • Phosphotransferases