Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jul 20;23(7):1795.
doi: 10.3390/molecules23071795.

Effect of Tea Catechins on Influenza Infection and the Common Cold With a Focus on Epidemiological/Clinical Studies

Free PMC article

Effect of Tea Catechins on Influenza Infection and the Common Cold With a Focus on Epidemiological/Clinical Studies

Daisuke Furushima et al. Molecules. .
Free PMC article


Influenza and the common cold are acute infectious diseases of the respiratory tract. Influenza is a severe disease that is highly infectious and can progress to life-threating diseases such as pneumonia or encephalitis when aggravated. Due to the fact that influenza infections and common colds spread easily via droplets and contact, public prevention measures, such as hand washing and facial masks, are recommended for influenza prophylaxis. Experimental studies have reported that tea catechins inhibited influenza viral adsorption and suppressed replication and neuraminidase activity. They were also effective against some cold viruses. In addition, tea catechins enhance immunity against viral infection. Although the antiviral activity of tea catechins has been demonstrated, the clinical evidence to support their utility remains inconclusive. Since the late 1990s, several epidemiological studies have suggested that the regular consumption of green tea decreases influenza infection rates and some cold symptoms, and that gargling with tea catechin may protect against the development of influenza infection. This review briefly summarizes the effect of tea catechins on influenza infection and the common cold with a focus on epidemiological/clinical studies, and clarifies the need for further studies to confirm their clinical efficacy.

Keywords: bioactivity; common cold; epidemiological study; influenza infection; tea catechins.

Conflict of interest statement

The authors declare no conflict of interest.

Similar articles

See all similar articles

Cited by 4 articles


    1. World Health Organization Fact Sheets Influenza (Seasonal) [(accessed on 1 April 2018)]; Available online:
    1. Rothberg M.B., Haessler S.D. Complications of seasonal and pandemic influenza. Crit. Care Med. 2010;38:e91–e97. doi: 10.1097/CCM.0b013e3181c92eeb. - DOI - PubMed
    1. Rothberg M.B., Haessler S.D., Brown R.B. Complications of viral influenza. Am. J. Med. 2008;121:258–264. doi: 10.1016/j.amjmed.2007.10.040. - DOI - PMC - PubMed
    1. Taubenberger J.K., Morens D.M. Influenza: The once and future pandemic. Public Health Rep. 2010;125:16–26. doi: 10.1177/00333549101250S305. - DOI - PMC - PubMed
    1. Aiello A.E., Murray G.F., Perez V., Coulborn R.M., Davis B.M., Uddin M., Shay D.K., Waterman S.H., Monto A.S. Mask use, hand hygiene, and seasonal influenza-like illness among young adults: A randomized intervention trial. J. Infect. Dis. 2010;201:491–498. doi: 10.1086/650396. - DOI - PubMed

MeSH terms