Optic Nerve Head Elastometry in Both Eyes of Patients with Unilateral Non-arteritic Anterior Ischaemic Optic Neuropathy - May It Be a Novel Aspect of the Pathogenesis?

Pinar Kosekahya; Mehtap Caglayan; Ozlem Unal; Sema Yuzbasioglu; Mustafa Koc; Cemile Ucgul Atilgan; Fatma Yulek

doi:10.1080/01658107.2017.1397702

Optic Nerve Head Elastometry in Both Eyes of Patients with Unilateral Non-arteritic Anterior Ischaemic Optic Neuropathy - May It Be a Novel Aspect of the Pathogenesis?

Neuroophthalmology. 2017 Nov 9;42(4):222-228. doi: 10.1080/01658107.2017.1397702. eCollection 2018 Aug.

Authors

Pinar Kosekahya¹, Mehtap Caglayan², Ozlem Unal³, Sema Yuzbasioglu⁴, Mustafa Koc¹, Cemile Ucgul Atilgan¹, Fatma Yulek⁵

Affiliations

¹ Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
² Department of Ophthalmology, Mardin State Hospital, Mardin, Turkey.
³ Department of Radiology, Ataturk Training and Research Hospital, Ankara, Turkey.
⁴ Department of Ophthalmology, Ataturk Training and Research Hospital, Ankara, Turkey.
⁵ Department of Ophthalmology, Yildirim Beyazit University Ataturk Research and Training Hospital, Ankara, Turkey.

Abstract

In this prospective study, the biomechanical properties of optic nerve head (ONH) and cornea in both eyes of patients with non-arteritic anterior ischaemic optic neuropathy and healthy control eyes were investigated. ONH elastometry was measured with real-time elastography, and corneal elastometry was measured with ocular response analyser. Elastometry of cornea and ONH was lower in both eyes of patients with unilateral non-arteritic ischaemic optic neuropathy than in healthy control eyes. The role of these biomechanical differences in the pathogenesis of non-arteritic ischaemic optic neuropathy should be investigated further.

Keywords: Corneal hysteresis; corneal resistance factor; non-arteritic anterior ischaemic neuropathy; optic nerve head biomechanics; real-time elastography.