Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075

AIDS Behav. 2019 Jan;23(1):289-294. doi: 10.1007/s10461-018-2231-1.

Abstract

Some HIV-infected individuals in research studies may choose not to disclose knowledge of their HIV status to study staff. We evaluated the accuracy of self-reported HIV status among African men and transgender women who have sex with men and who were screened for a research study. Sixty-seven of 183 HIV-infected participants reported a prior HIV diagnosis. Samples from the remaining 116 participants were tested for antiretroviral (ARV) drugs. Thirty-six of the 116 participants had ARV drugs detected, indicating that they were on antiretroviral treatment; these participants were classified as previously diagnosed based on ARV drug testing. Among participants classified as previously diagnosed, disclosure of a prior HIV diagnosis varied among study sites (p = 0.006) and was more common among those who reported having sex with men only (p = 0.002). ARV drug testing in addition to self-report improves the accuracy for identifying individuals with a prior HIV diagnosis.

Keywords: ART; Africa; HIV; MSM; Self-report; Transgender women.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Retroviral Agents / therapeutic use
  • Disclosure*
  • Female
  • HIV Infections / diagnosis*
  • HIV Infections / drug therapy
  • Homosexuality, Male
  • Humans
  • Kenya
  • Malawi
  • Male
  • Research
  • Self Report*
  • Sexual and Gender Minorities*
  • South Africa
  • Transgender Persons
  • Young Adult

Substances

  • Anti-Retroviral Agents