Validation in SPECT imaging on presynaptic dopaminergic deficit for dementia with Lewy bodies and degenerative Parkinsonism

J Neurol Sci. 2018 Sep 15:392:116. doi: 10.1016/j.jns.2018.07.017. Epub 2018 Jul 21.

Author

Tomoyuki Kawada¹

Affiliation

¹ Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-Ku, Tokyo 113-8602, Japan. Electronic address: kawada@nms.ac.jp.

PMID: 30055381
DOI: 10.1016/j.jns.2018.07.017

No abstract available

Keywords: Degenerative Parkinsonism; Dementia with Lewy bodies; Presynaptic dopaminergic deficit; SPECT imaging; Validation.

Publication types

Letter

MeSH terms

Dopamine / deficiency*
Humans
Lewy Body Disease / diagnostic imaging*
Lewy Body Disease / metabolism*
Neurodegenerative Diseases / complications
Neurodegenerative Diseases / diagnostic imaging*
Parkinson Disease / diagnostic imaging*
Parkinson Disease / etiology
Presynaptic Terminals / metabolism
Tomography, Emission-Computed, Single-Photon / methods*
Tropanes / pharmacokinetics

Substances

Tropanes
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane
Dopamine