Cyclic imide derivatives: As promising scaffold for the synthesis of antimicrobial agents

Farshid Hassanzadeh; Elham Jafari

doi:10.4103/jrms.JRMS_539_17

Cyclic imide derivatives: As promising scaffold for the synthesis of antimicrobial agents

J Res Med Sci. 2018 Jun 6:23:53. doi: 10.4103/jrms.JRMS_539_17. eCollection 2018.

Authors

Farshid Hassanzadeh¹, Elham Jafari²

Affiliations

¹ Department of Medicinal Chemistry, Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
² Department of Medicinal Chemistry, Bioinformatics Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Cyclic imides as building blocks in the synthesis of natural products, drugs and polymers display a diverse of pharmacological activities such as antibacterial, antifungal, anticonvulsant, anticancer, and anti-inflammatory effects. This review summarizes recent findings on antimicrobial activities of cyclic imide derivatives and emphasis on the importance of cyclic imides for drug design and development of new antimicrobial compounds.

Keywords: Antibacterial agents; antifungal agents; imides.

Publication types

Review