Antithrombotic therapy for patients with an indication for oral anticoagulation undergoing percutaneous coronary intervention with stent: The case of venous thromboembolism

Int J Cardiol. 2018 Oct 15:269:75-79. doi: 10.1016/j.ijcard.2018.07.133. Epub 2018 Jul 26.

Abstract

The management of antithrombotic therapy in patients on oral anticoagulation (OAC) for atrial fibrillation (AF) undergoing percutaneous coronary intervention with stent (PCI) is currently addressed by expert consensus documents and official Guidelines. No specific data, nor management suggestions, are available for OAC patients undergoing PCI in whom the indication for OAC is venous thromboembolism (VTE). In this article, the available evidence on VTE patients undergoing PCI, as obtained from studies where patients with various indications for PCI were included, is evaluated, and an algorithm for the management of antithrombotic therapy in this unique population is proposed.

Keywords: Oral anticoagulation; Percutaneous coronary intervention; Stent; Venous thromboembolism.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Anticoagulants / administration & dosage*
  • Anticoagulants / adverse effects
  • Atrial Fibrillation / diagnosis
  • Atrial Fibrillation / drug therapy
  • Atrial Fibrillation / surgery
  • Humans
  • Percutaneous Coronary Intervention / adverse effects
  • Percutaneous Coronary Intervention / trends*
  • Stents / adverse effects
  • Stents / trends*
  • Thrombolytic Therapy / adverse effects
  • Thrombolytic Therapy / trends*
  • Treatment Outcome
  • Venous Thromboembolism / diagnosis
  • Venous Thromboembolism / drug therapy*
  • Venous Thromboembolism / surgery*

Substances

  • Anticoagulants