Treating exercise-associated low testosterone and its related symptoms

Phys Sportsmed. 2018 Nov;46(4):427-434. doi: 10.1080/00913847.2018.1507234. Epub 2018 Aug 27.

Abstract

The Exercise-Hypogonadal Male Condition (EHMC) has been described to occur in athletes who experience low serum testosterone and associated symptoms. While high volumes of endurance exercise can lead to reduced testosterone concentrations in men, similar changes may occur in other sports including anerobic and power sports such as American football, and weight class sports such as wrestling. A reduced testosterone concentration alone does not necessarily warrant treatment, but when it is accompanied by symptoms of hypogonadism, such as fatigue, sexual dysfunction, and/or low bone mineral density (BMD), an athlete's performance and/or health may suffer. While pharmacological treatments such as testosterone or clomiphene citrate have been shown to be effective in treating hypogonadism, these options are not available to athletes competing in sports governed by the World Anti-Doping Agency. We recommend treatment of EHMC in athletes should include nutritional intervention and modification of training. Recognizing EHMC's existence in male athletes is important to optimize their health.

Keywords: Exercise-hypogonadal male condition; hypogonadism; overtraining; relative energy deficiency in sports.

Publication types

  • Review

MeSH terms

  • Adult
  • Athletes
  • Bone Density
  • Exercise*
  • Humans
  • Hypogonadism / diagnosis*
  • Hypogonadism / therapy
  • Male
  • Sports
  • Testosterone / blood*
  • Testosterone / deficiency

Substances

  • Testosterone