The use of computed tomography numbers in dose calculations for radiation therapy

Acta Radiol Oncol. 1985 Nov-Dec;24(6):509-19. doi: 10.3109/02841868509134425.

Abstract

Although corrections for 'beam hardening' and 'scattering' have been implemented in currently available CT scanners, systematic differences exist between a real CT image and an ideal, artefact-free and monochromatic image. The appearance and magnitude of these differences are discussed. Conversion to the ideal image, i.e. conversion from CT number to X-ray attenuation coefficient at diagnostic photon energies, turns out to be possible with an accuracy of 5 per cent. In order to use the CT 'density' information from patients, in clinical photon and electron beam dose calculations, conversions must be made from the X-ray attenuation coefficient at diagnostic energies to relevant high energy radiation interaction properties. These conversions turn out to be possible within an accuracy also of 5 per cent. These limited accuracies cause errors in the photon beam dose calculation of less than 1 per cent of the dose maximum and errors in electron beam dose calculations of less than 2 per cent of the dose maximum.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Mathematics
  • Neoplasms / diagnostic imaging
  • Neoplasms / radiotherapy*
  • Radiotherapy Dosage*
  • Tomography, X-Ray Computed / methods*