Xylitol Toxicosis in Dogs: An Update

Vet Clin North Am Small Anim Pract. 2018 Nov;48(6):985-990. doi: 10.1016/j.cvsm.2018.06.004. Epub 2018 Jul 29.


Xylitol ingestions in dogs may result in severe hypoglycemia followed by acute hepatic failure and associated coagulopathies. Aggressive treatment may be needed, but the prognosis is generally expected to be good for dogs developing uncomplicated hypoglycemia. Because of increased availability of xylitol-containing products in the market and in the dog's environment, it is likely that there will continue to be increased exposures and toxicity in dogs.

Keywords: Coagulopathy; Hypoglycemia; Liver failure; Xylitol.

Publication types

  • Review

MeSH terms

  • Animals
  • Dog Diseases / chemically induced*
  • Dog Diseases / therapy
  • Dogs
  • Hypoglycemia / chemically induced
  • Hypoglycemia / therapy
  • Hypoglycemia / veterinary*
  • Liver Failure, Acute / complications
  • Liver Failure, Acute / veterinary
  • Prognosis
  • Sweetening Agents / pharmacology
  • Sweetening Agents / toxicity*
  • Xylitol / pharmacology
  • Xylitol / toxicity*


  • Sweetening Agents
  • Xylitol