Rates of Overtreatment and Treatment-Related Adverse Effects Among Patients With Subsegmental Pulmonary Embolism

doi:10.1001/jamainternmed.2018.2971

. 2018 Sep 1;178(9):1272-1274.

doi: 10.1001/jamainternmed.2018.2971.

Rates of Overtreatment and Treatment-Related Adverse Effects Among Patients With Subsegmental Pulmonary Embolism

Ismail A Raslan¹, Jaron Chong², Benoît Gallix², Todd C Lee^{3

4}, Emily G McDonald^{3

4}

Affiliations

¹ Faculty of Medicine, McGill University, Montréal, Quebec, Canada.
² Department of Radiology, McGill University Health Centre, Montréal, Quebec, Canada.
³ Department of Medicine, McGill University Health Centre, Montréal, Quebec, Canada.
⁴ Clinical Practice Assessment Unit, McGill University Health Centre, Montréal, Quebec, Canada.

PMID: 30073241
PMCID: PMC6142970
DOI: 10.1001/jamainternmed.2018.2971

Rates of Overtreatment and Treatment-Related Adverse Effects Among Patients With Subsegmental Pulmonary Embolism

Ismail A Raslan et al. JAMA Intern Med. 2018.

. 2018 Sep 1;178(9):1272-1274.

doi: 10.1001/jamainternmed.2018.2971.

Authors

Ismail A Raslan¹, Jaron Chong², Benoît Gallix², Todd C Lee^{3

4}, Emily G McDonald^{3

4}

Affiliations

¹ Faculty of Medicine, McGill University, Montréal, Quebec, Canada.
² Department of Radiology, McGill University Health Centre, Montréal, Quebec, Canada.
³ Department of Medicine, McGill University Health Centre, Montréal, Quebec, Canada.
⁴ Clinical Practice Assessment Unit, McGill University Health Centre, Montréal, Quebec, Canada.

PMID: 30073241
PMCID: PMC6142970
DOI: 10.1001/jamainternmed.2018.2971

Abstract

This cohort study examines how often clinicians opt for clinical surveillance over therapeutic anticoagulation for patients with subsegmental pulmonary embolisms.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Comment in

Are We Overtreating Isolated Subsegmental Pulmonary Embolism?: First Do No Harm.
Moores LK. Moores LK. JAMA Intern Med. 2018 Sep 1;178(9):1274-1275. doi: 10.1001/jamainternmed.2018.2970. JAMA Intern Med. 2018. PMID: 30073302 No abstract available.

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References

1. Pena E, Kimpton M, Dennie C, Peterson R, LE Gal G, Carrier M. Difference in interpretation of computed tomography pulmonary angiography diagnosis of subsegmental thrombosis in patients with suspected pulmonary embolism. J Thromb Haemost. 2012;10(3):496-498. doi:10.1111/j.1538-7836.2011.04612.x - DOI - PubMed
1. Wiener RS, Schwartz LM, Woloshin S. Time trends in pulmonary embolism in the United States: evidence of overdiagnosis. Arch Intern Med. 2011;171(9):831-837. doi:10.1001/archinternmed.2011.178 - DOI - PMC - PubMed
1. Carrier M, Righini M, Le Gal G. Symptomatic subsegmental pulmonary embolism: what is the next step? J Thromb Haemost. 2012;10(8):1486-1490. doi:10.1111/j.1538-7836.2012.04804.x - DOI - PubMed
1. Chong J, Lee TC, Attarian A, et al. . Association of lower diagnostic yield with high users of CT pulmonary angiogram. JAMA Intern Med. 2018;178(3):412-413. doi:10.1001/jamainternmed.2017.7552 - DOI - PMC - PubMed
1. Kearon C, Akl EA, Ornelas J, et al. . Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report. Chest. 2016;149(2):315-352. doi:10.1016/j.chest.2015.11.026 - DOI - PubMed

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[1] Pena E, Kimpton M, Dennie C, Peterson R, LE Gal G, Carrier M. Difference in interpretation of computed tomography pulmonary angiography diagnosis of subsegmental thrombosis in patients with suspected pulmonary embolism. J Thromb Haemost. 2012;10(3):496-498. doi:10.1111/j.1538-7836.2011.04612.x - DOI - PubMed

[2] Pena E, Kimpton M, Dennie C, Peterson R, LE Gal G, Carrier M. Difference in interpretation of computed tomography pulmonary angiography diagnosis of subsegmental thrombosis in patients with suspected pulmonary embolism. J Thromb Haemost. 2012;10(3):496-498. doi:10.1111/j.1538-7836.2011.04612.x - DOI - PubMed

[3] Wiener RS, Schwartz LM, Woloshin S. Time trends in pulmonary embolism in the United States: evidence of overdiagnosis. Arch Intern Med. 2011;171(9):831-837. doi:10.1001/archinternmed.2011.178 - DOI - PMC - PubMed

[4] Wiener RS, Schwartz LM, Woloshin S. Time trends in pulmonary embolism in the United States: evidence of overdiagnosis. Arch Intern Med. 2011;171(9):831-837. doi:10.1001/archinternmed.2011.178 - DOI - PMC - PubMed

[5] Carrier M, Righini M, Le Gal G. Symptomatic subsegmental pulmonary embolism: what is the next step? J Thromb Haemost. 2012;10(8):1486-1490. doi:10.1111/j.1538-7836.2012.04804.x - DOI - PubMed

[6] Carrier M, Righini M, Le Gal G. Symptomatic subsegmental pulmonary embolism: what is the next step? J Thromb Haemost. 2012;10(8):1486-1490. doi:10.1111/j.1538-7836.2012.04804.x - DOI - PubMed

[7] Chong J, Lee TC, Attarian A, et al. . Association of lower diagnostic yield with high users of CT pulmonary angiogram. JAMA Intern Med. 2018;178(3):412-413. doi:10.1001/jamainternmed.2017.7552 - DOI - PMC - PubMed

[8] Chong J, Lee TC, Attarian A, et al. . Association of lower diagnostic yield with high users of CT pulmonary angiogram. JAMA Intern Med. 2018;178(3):412-413. doi:10.1001/jamainternmed.2017.7552 - DOI - PMC - PubMed

[9] Kearon C, Akl EA, Ornelas J, et al. . Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report. Chest. 2016;149(2):315-352. doi:10.1016/j.chest.2015.11.026 - DOI - PubMed

[10] Kearon C, Akl EA, Ornelas J, et al. . Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report. Chest. 2016;149(2):315-352. doi:10.1016/j.chest.2015.11.026 - DOI - PubMed

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Rates of Overtreatment and Treatment-Related Adverse Effects Among Patients With Subsegmental Pulmonary Embolism

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Rates of Overtreatment and Treatment-Related Adverse Effects Among Patients With Subsegmental Pulmonary Embolism

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