Spatial restriction in expression of a mouse homoeo box locus within the central nervous system

Nature. 1986 Mar 27-Apr 2;320(6060):328-35. doi: 10.1038/320328a0.


A common feature of Drosophila homoeo box genes appears to be their spatially restricted expression patterns during morphogenesis. Using Northern blot analysis and in situ hybridization to mouse tissue sections, the spatially restricted expression of a newly identified mouse homoeo box locus, Hox-3, within the central nervous system of newborn and adult mice has been demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Age Factors
  • Animals
  • Animals, Newborn
  • Central Nervous System / growth & development
  • Central Nervous System / physiology*
  • Chromosome Mapping
  • Cloning, Molecular
  • DNA Restriction Enzymes / metabolism
  • Gene Expression Regulation*
  • Mice / genetics*
  • Mice / growth & development
  • Morphogenesis
  • Nucleic Acid Hybridization
  • RNA, Messenger / genetics
  • Tissue Distribution


  • RNA, Messenger
  • DNA Restriction Enzymes

Associated data

  • GENBANK/X03659