Risk of total knee arthroplasty in young and middle-aged adults with ankylosing spondylitis

Michael M Ward

doi:10.1007/s10067-018-4246-4

Risk of total knee arthroplasty in young and middle-aged adults with ankylosing spondylitis

Clin Rheumatol. 2018 Dec;37(12):3431-3433. doi: 10.1007/s10067-018-4246-4. Epub 2018 Aug 7.

Author

Michael M Ward¹

Affiliation

¹ Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, NIAMS/NIH, Building 10 CRC, Room 4-1339, 10 Center Drive, Bethesda, MD, 20892-1468, USA. wardm1@mail.nih.gov.

Abstract

The objective was to determine the risk of primary total knee arthroplasty (TKA) in young and middle-aged adults with ankylosing spondylitis (AS). We computed arthroplasty rates among US Medicaid recipients age 18 to 64 with AS and a comparison group without AS from 1999 to 2011. Among 14,714 patients with AS and 2,932,641 patients without AS, rates of primary TKA were 1.82-fold higher (95% confidence interval 1.57, 2.10) among patients with AS. The risk of primary TKA is elevated in young and middle-aged adults with AS.

Keywords: Ankylosing spondylitis; Total knee arthroplasty.

MeSH terms

Adolescent
Adult
Arthroplasty, Replacement, Knee / methods*
Databases, Factual
Female
Humans
Incidence
Male
Medicaid
Middle Aged
Osteoarthritis, Knee / complications
Osteoarthritis, Knee / surgery*
Postoperative Complications
Retrospective Studies
Risk
Spondylitis, Ankylosing / complications
Spondylitis, Ankylosing / surgery*
United States
Young Adult

Abstract

MeSH terms

Grants and funding