Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Sep;118(3):581-587.
doi: 10.1002/jso.25168. Epub 2018 Aug 10.

Surgical Oncology at a Major Referral Center in Ghana: Burden, Staging, and Outcomes

Affiliations
Free PMC article

Surgical Oncology at a Major Referral Center in Ghana: Burden, Staging, and Outcomes

Adam Gyedu et al. J Surg Oncol. .
Free PMC article

Abstract

Background and objectives: Outcome data after surgery for cancer in Sub-Saharan Africa are insufficient. We aimed to describe the presentation and outcomes of patients with solid cancers managed at a tertiary hospital in Ghana.

Methods: Records of cancer patients admitted to Komfo Anokye Teaching Hospital general surgery wards from 2013 to 2016 were reviewed for data on presentation, staging, management, and mortality. Patients discharged alive were followed-up by biannual telephone calls to establish their postdischarge status. Survival analysis was performed for patients with pathologic or radiologic confirmation of cancer and adequate staging.

Results: A total of 343 patients were included. Of these, 76% were female. The most common diagnoses were breast 136 (40%), foregut 70 (20%), and colorectal 63 (18%) cancers. Cancer diagnosis was confirmed by pathology or radiology in 281 (82%) patients, but only 112 (40%) had adequate staging. Seventy-four (66%) patients were stage IV. Two-year overall survival for all 343 patients was 22% to 69%, depending on cancer site. Among those with adequate staging who were alive after postoperative 90 days, 3-year survival was similar for curative compared with palliative operations (P = 0.64).

Conclusions: Improved capacity for both therapeutic and palliative cancer care is needed to achieve better outcomes by more appropriate allocation of surgery with respect to the goal of treatment.

Keywords: Ghana; cancer; low- and middle-income counties; outcomes; surgery.

Conflict of interest statement

Conflict of Interests

None

Figures

Figure 1.
Figure 1.
Description of patients.
Figure 2.
Figure 2.. Overall survival from initial presentation by cancer site.
Hash marks indicate points of censorship, due to participants being lost to follow up.
Figure 3:
Figure 3:. Survival after post-operative 90 days by operative intent among patients with adequate staging.
Hash marks indicate points of censorship, due to participants being lost to follow up.

Similar articles

See all similar articles

Cited by 1 article

LinkOut - more resources

Feedback