Sequencing Diversity One Cell at a Time

Cell. 2018 Aug 9;174(4):777-779. doi: 10.1016/j.cell.2018.07.024.


Single-cell RNA sequencing provides a new approach to an old problem: how to study cellular diversity in complex biological systems. Three studies-Saunders et al., Zeisel et al., and Davie et al.-deploy this technique on an unprecedented scale to reveal transcriptional patterns that distinguish cells in the nervous systems of mice and flies.

Publication types

  • Comment

MeSH terms

  • Animals
  • Base Sequence
  • Brain
  • Drosophila*
  • Mice
  • Sequence Analysis, RNA
  • Transcriptome*