The characteristics of a preservative-free contact lens care solution on lysozyme adsorption and interfacial friction behavior

Colloids Surf B Biointerfaces. 2018 Nov 1:171:538-543. doi: 10.1016/j.colsurfb.2018.07.076. Epub 2018 Aug 3.

Abstract

The population of soft contact lens wearers is increasing, thus the issues of feeling comfortable and contact lens-induced clinical symptoms are concerned. Both lysozyme deposition and mechanical friction among contact lens and the eye can induce discomfort and eye conditions. Therefore, we characterized our developed preservative-free contact lens care solution on lysozyme adsorption and lubrication. Two distinct lens materials were washed with the care solution after being soaked in lysozyme, as well as were rubbed against the glass in the presence of lysozyme and the care solution for measuring the friction coefficient. Our results demonstrated that the preservative-free contact lens care solution can be applied as a potential lubricant for a specific type of soft contact lenses.

Keywords: Contact lens care solution; Lubrication; Lysozyme; Soft contact lens.

MeSH terms

  • Adsorption
  • Contact Lens Solutions / chemistry*
  • Muramidase / chemistry*
  • Muramidase / metabolism
  • Particle Size
  • Solutions
  • Surface Properties

Substances

  • Contact Lens Solutions
  • Solutions
  • Muramidase