Type 1 Diabetes Mellitus Diagnosed during Follow-up of Gestational Diabetes Mellitus in the Early Postpartum Period

Intern Med. 2018 Dec 1;57(23):3413-3418. doi: 10.2169/internalmedicine.1188-18. Epub 2018 Aug 10.


A 27-year-old woman with a history of gestational diabetes mellitus (GDM) developed type 1 diabetes mellitus (T1D) in the early postpartum period. Women with a history of GDM are at an increased risk of developing T1D, which is rarer than type 2 diabetes mellitus. A postpartum follow-up 75-g oral glucose tolerance test and the measurement of glutamic acid decarboxylase autoantibodies aided in the early detection of T1D in this patient. Careful attention should be paid to women with a history of GDM who exhibit clinical features suggestive of future development of T1D.

Keywords: gestational diabetes mellitus; postpartum; slowly progressive type 1 diabetes mellitus; type 1 diabetes mellitus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autoantibodies / blood
  • Diabetes Mellitus, Type 1 / diagnosis*
  • Diabetes Mellitus, Type 1 / enzymology
  • Diabetes, Gestational / diagnosis*
  • Early Diagnosis
  • Female
  • Follow-Up Studies
  • Glucose Tolerance Test
  • Glutamate Decarboxylase / immunology
  • Humans
  • Postpartum Period*
  • Pregnancy
  • Risk Factors


  • Autoantibodies
  • Glutamate Decarboxylase