Updates on Diabetic Foot and Charcot Osteopathic Arthropathy

Curr Diab Rep. 2018 Aug 15;18(10):74. doi: 10.1007/s11892-018-1047-8.


Purpose of review: Diabetes mellitus affects approximately 30.8 million people currently living in the USA. Chronic diabetes complications, including diabetic foot complications, remain prevalent and challenging to treat. We review clinical diagnosis and challenges providers may encounter when managing diabetic foot ulcers and Charcot neuroarthropathy.

Recent findings: Mechanisms controlling these diseases are being elucidated and not fully understood. Offloading is paramount to heal and manage diabetic foot ulcers and Charcot neuroarthropathy. Diabetic foot ulcers recur and the importance of routine surveillance and multidisciplinary approach is essential. Several predictors of failure in Charcot foot include a related diabetic foot ulcer, midfoot or rearfoot location of the Charcot event, and progressive bony changes on interval radiographs. Patients with diabetic foot ulcer and/or Charcot neuroarthropathy are in need of consistent and regular special multidisciplinary care. If not diagnosed early and managed effectively, morbidity and mortality significantly increase.

Keywords: Charcot osteopathic arthropathy; Diabetic foot; Infection; Limb salvage; Neuropathic ulcers; Podiatry.

Publication types

  • Review

MeSH terms

  • Arthropathy, Neurogenic / pathology*
  • Diabetic Foot / classification
  • Diabetic Foot / diagnosis
  • Diabetic Foot / pathology*
  • Early Diagnosis
  • Humans
  • Inflammation / pathology
  • Treatment Outcome
  • Wound Healing