Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence

PLoS One. 2018 Aug 16;13(8):e0201167. doi: 10.1371/journal.pone.0201167. eCollection 2018.

Abstract

Aims: Our aim was to evaluate, in a second data analysis of the prospective randomized controlled trial conducted by Austrian Urogynaecology Working Group, the effect of age, BMI and parity at the time of surgery on short- and long-term outcomes of women primarily treated for SUI (stress urinary incontinence) with midurethral slings.

Methods: In the original study 554 patients received randomly a retropubic (TVT) or a transobturator midurethral (TVT-O) sling procedure. 480 (87%) and 277 (50%) patients were available for a follow-up efficacy evaluation at 3 months and 5 years respectively.

Results: Higher age and BMI at surgery appear to lead to a larger probability to have a positive stress test 5 years after surgery, but not after 3 months. Older patients seem to have a worse perception of improvement 5 years after surgery as compared to younger ones, as described by the PGI-I score. Age and BMI do not affect significantly the quality of life of women surgically treated for SUI, as reflected by the results of King´s Health Questionnaire. Parity does not seem to have any effect on objective and subjective surgical outcomes.

Conclusions: Higher age and BMI at surgery have a detrimental influence on the objective cure rate at 5 years after midurethral sling surgery; higher age also has a negative influence on subjective long-term outcomes. However, these demographic parameters do not influence significantly the quality of life of patients after anti-incontinence surgery. Parity does not show any significant influence on success rate of midurethral sling.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Austria
  • Body Mass Index
  • Data Interpretation, Statistical
  • Female
  • Humans
  • Middle Aged
  • Parity
  • Pregnancy
  • Prospective Studies
  • Quality of Life
  • Suburethral Slings*
  • Treatment Outcome
  • Urinary Incontinence, Stress / surgery*

Grant support

Financial support was provided by Austrian Urogynecology Working Group and the Karl-Landsteiner-Institut fuer Spezielle Gynaekologie und Geburtshilfe of Vienna. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.