Reactive hemophagocytic syndrome in the setting of acute human immunodeficiency virus 1 infection: case report and review of the literature

Luis G Tulloch; Ramee Younes; Arthur Jeng

doi:10.1177/0956462418788689

Reactive hemophagocytic syndrome in the setting of acute human immunodeficiency virus 1 infection: case report and review of the literature

Int J STD AIDS. 2018 Nov;29(13):1354-1358. doi: 10.1177/0956462418788689. Epub 2018 Aug 16.

Authors

Luis G Tulloch¹, Ramee Younes², Arthur Jeng^{1

3}

Affiliations

¹ 1 UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
² 2 Department of Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USA.
³ 3 Department of Medicine, Division of Infectious Diseases, Olive View-UCLA Medical Center, Sylmar, CA, USA.

PMID: 30114998
DOI: 10.1177/0956462418788689

Abstract

We report a case of reactive hemophagocytic syndrome (RHS) in the setting of acute human immunodeficiency virus type 1 infection (AHI). In addition, we review 11 previously reported cases of RHS precipitated by AHI and discuss strategies in the diagnosis and management of these overlapping clinical entities.

Keywords: Reactive hemophagocytic syndrome; human immunodeficiency virus.

Publication types

Case Reports
Review

MeSH terms

Adrenal Cortex Hormones / therapeutic use
Adult
Anti-Retroviral Agents / therapeutic use
Etoposide / therapeutic use
Exanthema / etiology
HIV Infections / diagnosis*
HIV Infections / drug therapy
HIV-1 / immunology*
Histiocytosis / diagnosis*
Histiocytosis / drug therapy
Humans
Injections, Spinal
Lymphohistiocytosis, Hemophagocytic / diagnosis*
Lymphohistiocytosis, Hemophagocytic / drug therapy
Male
Methotrexate / therapeutic use
Treatment Outcome

Substances

Adrenal Cortex Hormones
Anti-Retroviral Agents
Etoposide
Methotrexate