Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis

Dermatol Pract Concept. 2018 Jul 31;8(3):184-187. doi: 10.5826/dpc.0803a07. eCollection 2018 Jul.

Abstract

We present a case of subcutaneous nodular amyloidosis mimicking a pilar cyst. Further evaluation led to the diagnosis of malignant systemic light-chain amyloidosis. The epidemiology and histopathological features of light-chain amyloidosis with cutaneous involvement are reviewed, as well as current recommendations for initial evaluation.

Keywords: nodular amyloidosis; pilar cyst; subcutaneous nodule; systemic AL amyloidosis.