Use of infragluteal folds as a full-thickness skin graft donor site for construction of the neovagina in cases of Mullerian agenesis

J Obstet Gynaecol Res. 2018 Oct;44(10):1985-1994. doi: 10.1111/jog.13752. Epub 2018 Aug 16.

Abstract

Aim: The aims of this study were to present the results of using infragluteal folds as a skin graft donor site in cases of Mullerian agenesis undergoing full-thickness skin graft vaginoplasty and to evaluate the outcomes of the surgical technique.

Methods: Demographics and clinical parameters of 24 consecutive Mullerian agenesis patients refusing any dilatational procedure and undergoing neovaginal construction using infragluteal folds skin grafts from May 2004 to July 2015 were analyzed.

Results: The mean age of the patients was 21.5 ± 5.7 years. Five patients had nonfunctional rudimentary uterus, one patient had unilateral ovarian agenesis, one patient had unilateral renal agenesis, and one had undergone a previous vaginoplasty. There were no serious complications needing surgical or medical intervention. The depth of the neovagina in patients with a follow-up period of more than 6 months (n = 17) varied from 7 to 12 cm. Of these patients, the sexually active ones (n = 8) did not complain of dyspareunia or vaginal dryness during sexual intercourse. The resulting scars were satisfactory and acceptable for all patients.

Conclusion: It has been our practice to use infragluteal folds as a skin graft donor site for full-thickness skin graft vaginoplasty. We believe that the results of this study demonstrate that this area is versatile and an excellent alternative to the groins and lower abdomen. Further clinical and histomorphological investigations are necessary for strong statements and results.

Keywords: Mullerian aplasia-dysgenesis; gluteal region; reconstructive surgery; skin grafting; vaginal agenesis.

MeSH terms

  • 46, XX Disorders of Sex Development / pathology
  • 46, XX Disorders of Sex Development / surgery*
  • Adolescent
  • Adult
  • Congenital Abnormalities / pathology
  • Congenital Abnormalities / surgery*
  • Female
  • Gynecologic Surgical Procedures / methods*
  • Humans
  • Mullerian Ducts / abnormalities*
  • Mullerian Ducts / pathology
  • Mullerian Ducts / surgery
  • Plastic Surgery Procedures / methods*
  • Skin Transplantation / methods*
  • Urogenital Abnormalities / surgery*
  • Vagina / abnormalities
  • Vagina / surgery*
  • Young Adult

Supplementary concepts

  • Mullerian aplasia