Density-dependent determination of scattering properties of pharmaceutical tablets using coherent backscattering spectroscopy

Opt Express. 2018 Aug 6;26(16):19964-19971. doi: 10.1364/OE.26.019964.

Abstract

We report on measurements of coherent backscattering from pharmaceutical tablets. Experimental data is analysed using the radiative transfer equation with focus on the determination of the reduced scattering coefficient μs'. The results show a good agreement with μs' determined by measuring the spatially resolved reflectance, whereat we demonstrate advantages of the coherent backscattering measurements. Furthermore, we present a correlation between μs' and tablet compression force, respectively density.