Botryoid Rhabdomyosarcoma of the Conjunctiva in a Young Boy

Middle East Afr J Ophthalmol. 2018 Apr-Jun;25(2):111-114. doi: 10.4103/meajo.MEAJO_8_18.


Primary conjunctival rhabdomyosarcoma (RMS) is a rare entity that can present with or without papillomatous features. A 5-year-old Asian boy was referred for a rapidly growing conjunctival tumor in the superior fornix of the left eye. Surgical excision yielded a 28 mm multilobulated papillomatous specimen that exhibited histopathologic and immunohistochemical features consistent with embryonal (botryoid) RMS. Molecular analysis revealed the absence of the PAX3/FOXO1 fusion gene, indicating favorable prognosis. After surgery, he was promptly treated with systemic chemotherapy and proton beam radiotherapy.

Keywords: Botryoid; conjunctiva; papilloma; rhabdomyosarcoma; tumor.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Child, Preschool
  • Conjunctiva / pathology*
  • Conjunctival Neoplasms / diagnosis*
  • Humans
  • Male
  • Rhabdomyosarcoma / diagnosis*