Abstract
Remarkable advances have been made in the identification of the promoter regions for the ribosomal RNA genes from lower and higher eukaryotes. There has been some progress in the elucidation of the factors that control transcription of the ribosomal RNA gene. The characterization of the transcription factors are crucial for the understanding of the molecular mechanisms of ribosomal gene expression.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Adenosine Diphosphate Ribose / metabolism
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Animals
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Base Sequence
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Cell-Free System
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DNA Topoisomerases, Type I / metabolism
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DNA, Ribosomal / genetics
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DNA, Superhelical / genetics
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DNA, Superhelical / metabolism
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Drosophila melanogaster
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Enhancer Elements, Genetic*
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Genes, Regulator*
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Humans
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Liver Neoplasms, Experimental / metabolism
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Mice
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Promoter Regions, Genetic
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RNA Polymerase I / metabolism
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RNA Processing, Post-Transcriptional
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RNA, Ribosomal / biosynthesis*
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RNA, Ribosomal / genetics
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Rats
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Transcription Factors / metabolism
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Transcription, Genetic
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Xenopus laevis
Substances
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DNA, Ribosomal
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DNA, Superhelical
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RNA, Ribosomal
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Transcription Factors
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Adenosine Diphosphate Ribose
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RNA Polymerase I
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DNA Topoisomerases, Type I