Case of Early Amyotrophic Lateral Sclerosis With Prominent Magnetic Resonance Imaging Plexus Abnormalities

J Clin Neuromuscul Dis. 2018 Sep;20(1):41-44. doi: 10.1097/CND.0000000000000206.


Amyotrophic lateral sclerosis is a neurodegenerative disorder, which is characterized by progressive upper and lower motor neuron signs and symptoms, resulting in progressive muscle weakness. There are very rare reports of magnetic resonance imaging (MRI) abnormalities within the nerve roots or plexus reported in amyotrophic lateral sclerosis. Here, we report a patient who presented with progressive left arm weakness and was found to have bilateral MRI plexus abnormalities. This report illustrates that MRI plexus abnormalities can be seen in amyotrophic lateral sclerosis, possibly before symptoms, and may have clinical value in the diagnostic process.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyotrophic Lateral Sclerosis / diagnostic imaging*
  • Amyotrophic Lateral Sclerosis / drug therapy
  • Amyotrophic Lateral Sclerosis / physiopathology
  • Brachial Plexus / diagnostic imaging*
  • Electromyography
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Magnetic Resonance Imaging / methods*
  • Male
  • Neurologic Examination


  • Immunoglobulins, Intravenous