New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica

Xia Wang; Xing-Rong Peng; Jing Lu; Gui-Lin Hu; Ming-Hua Qiu

doi:10.1007/s13659-018-0181-y

New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica

Nat Prod Bioprospect. 2018 Dec;8(6):413-418. doi: 10.1007/s13659-018-0181-y. Epub 2018 Aug 20.

Authors

Xia Wang^{1

2}, Xing-Rong Peng¹, Jing Lu^{1

2}, Gui-Lin Hu^{1

2}, Ming-Hua Qiu^{3

4}

Affiliations

¹ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.
² University of the Chinese Academy of Sciences, Beijing, 100049, People's Republic of China.
³ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China. mhchiu@mail.kib.ac.cn.
⁴ University of the Chinese Academy of Sciences, Beijing, 100049, People's Republic of China. mhchiu@mail.kib.ac.cn.

Abstract

In present study, four new dammarane-type triterpenoids, namely caffruones A-D (1-4), were isolated from the cherries of Coffea arabica. Their structures were elucidated by extensive spectroscopic analysis including 1D, 2D NMR (HSQC, HMBC, ¹H-¹H COSY, and ROESY), HRMS and IR spectra. This is the first time that tetracyclic triterpenes have been reported in genus Coffea.

Keywords: Cherries; Coffea arabica; Structural elucidation; Triterpenoids.