Radical activation of carbon tetrachloride in foetal and maternal rat liver microsomes

Biochem Pharmacol. 1986 Jun 15;35(12):2041-4. doi: 10.1016/0006-2952(86)90739-2.
No abstract available

MeSH terms

  • Animals
  • Biotransformation
  • Calcium / metabolism
  • Carbon Tetrachloride / metabolism*
  • Cytochrome P-450 Enzyme System / analysis
  • Electron Spin Resonance Spectroscopy
  • Female
  • Fetus / drug effects
  • Fetus / metabolism*
  • Free Radicals
  • In Vitro Techniques
  • Lipid Peroxides / metabolism
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / metabolism*
  • NADP / metabolism
  • Pregnancy
  • Rats
  • Rats, Inbred Strains

Substances

  • Free Radicals
  • Lipid Peroxides
  • NADP
  • Cytochrome P-450 Enzyme System
  • Carbon Tetrachloride
  • Calcium