Combined carbon dioxide laser and cryosurgical ablation of rostral nasal septum squamous cell carcinoma in 10 dogs

Vet Dermatol. 2018 Oct;29(5):431-e142. doi: 10.1111/vde.12683. Epub 2018 Aug 21.

Abstract

Background: Squamous cell carcinoma (SCC) is the most commonly reported neoplasm of the nasal planum and treatment is focused on localized disease. Rostral maxillectomy and/or nasal planectomy are considered standard of care for excision of nasal planum SCC; however, the cosmetic outcome of these procedures can be deemed unacceptable by many pet owners.

Objectives: The study aim was to evaluate the efficacy of combination carbon dioxide (CO2 ) laser surgery and cryosurgery as a palliative treatment modality in dogs with nasal SCCs.

Animals: Ten client-owned dogs with nasal SCC were included: seven neutered males, two spayed females and one intact male, with a median age of 12.5 years (range 9-15 years).

Methods and materials: Tumour CO2 laser ablation was followed by cryosurgical ablation of the visible tumour, adjacent and subjacent tissue. Three rapid freeze-slow thaw cycles were performed.

Results: Eight of 10 dogs were Labrador retrievers. The ages ranged from 9 to 14 years. Overall median survival time was 260 days with two dogs still alive at the time of writing.

Conclusions and clinical importance: Combined CO2 laser and cryosurgical ablation was practical, cost-effective and provided an excellent aesthetic outcome in dogs with SCCs restricted to the nasal septum, while providing acceptable palliation of local disease.

MeSH terms

  • Animals
  • Carcinoma, Squamous Cell / surgery
  • Carcinoma, Squamous Cell / veterinary*
  • Cryosurgery / methods
  • Cryosurgery / veterinary*
  • Dog Diseases / surgery*
  • Dogs
  • Female
  • Lasers, Gas / therapeutic use*
  • Male
  • Nasal Septum* / surgery
  • Nose Neoplasms / surgery
  • Nose Neoplasms / veterinary*