Cyst Fluid Biomarkers - Diagnosis and Prediction of Malignancy for Cystic Lesions of the Pancreas

Aadhithya Raman; Anne Marie Lennon

doi:10.1159/000490137

Cyst Fluid Biomarkers - Diagnosis and Prediction of Malignancy for Cystic Lesions of the Pancreas

Visc Med. 2018 Jul;34(3):178-181. doi: 10.1159/000490137. Epub 2018 Jun 13.

Authors

Aadhithya Raman¹, Anne Marie Lennon¹

Affiliation

¹ Department of Medicine, Surgery, Radiology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Abstract

Pancreatic cysts are common, and are identified in 2-13% of individuals undergoing cross-sectional imaging. Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs) are pancreatic cysts which are precursors to pancreatic adenocarcinoma. Currently available tools are imperfect at differentiating IPMNs and MCNs from other, benign types of pancreatic cysts. The role of molecular markers in the evaluation of pancreatic cysts and the identification of cysts with high-grade dysplasia or invasive adenocarcinoma is reviewed.

Keywords: Biomarkers; Intraductal papillary mucinous neoplasm; Mucinous cystic neoplasm; Pancreatic cysts; Serous cystadenomas.

Publication types

Review

Abstract

Publication types

Grants and funding