Reviewing the use of imiquimod for molluscum contagiosum

Dermatol Online J. 2018 Aug 23;24(6):13030/qt3b4606qt.


We discuss imiquimod associated with non-application site mucosal reactions and two of our own clinical cases. In one of our patients, erosive cheilitis developed in a young boy after using topical imiquimod 5% cream for 5 nights weekly on bilateral cheeks, chin, and near vermillion border for molluscum contagiosum. The case is discussed with concerns for imiquimod use in molluscum contagiosum when used near mucosal surfaces.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adjuvants, Immunologic / adverse effects
  • Adjuvants, Immunologic / therapeutic use*
  • Cheilitis / chemically induced*
  • Cheilitis / etiology
  • Child
  • Humans
  • Imiquimod / adverse effects
  • Imiquimod / therapeutic use*
  • Male
  • Molluscum Contagiosum / drug therapy*


  • Adjuvants, Immunologic
  • Imiquimod