Parotid gland chondroma masquerading as pleomorphic adenoma in fine needle aspiration cytology: A diagnostic challenge

Diagn Cytopathol. 2018 Dec;46(12):1060-1063. doi: 10.1002/dc.24051. Epub 2018 Aug 25.

Abstract

Chondroid neoplasm of parotid gland is extremely rare. Only a few cases of extraskeletal chondroma and one case of chondrosarcoma of parotid gland have been reported in the literature. The cytological features of parotid gland chondroma are not well documented. A 61-year female patient presented with a slow growing left preauricular mass for past 6 years. Computer tomography scan showed a well circumscribed mass in the superficial lobe of left parotid gland. Fine needle aspiration cytology (FNAC) showed uniform chondrocytes embedded in a chondroid matrix, and was diagnosed as pleomorphic adenoma. Histological examination of the excised specimen showed a benign cartilaginous tumor, consistent with chondroma. There was no epithelial or myoepithelial component on extensive search. Chondroma is an extremely rare tumor of parotid gland and can be misdiagnosed as pleomorphic adenoma on cytology examination. However, absence of epithelial and myoepithelial component can give a clue toward a pure chondroid neoplasm. This report highlights the diagnostic features of chondroma of parotid gland and its diagnostic pitfalls in FNAC.

Keywords: chondroma; fine needle aspiration cytology; parotid gland; pleomorphic adenoma.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Pleomorphic / diagnosis
  • Adenoma, Pleomorphic / pathology
  • Biopsy, Fine-Needle / methods
  • Chondroma / diagnosis*
  • Chondroma / pathology*
  • Cytodiagnosis / methods
  • Diagnosis, Differential
  • Female
  • Humans
  • Middle Aged
  • Parotid Gland / pathology*
  • Parotid Neoplasms / diagnosis*
  • Parotid Neoplasms / pathology*