Psychometric Validation of the Czech Version of the Quality of Life - Alzheimer's Disease Scale in Patients with Early-Stage Dementia

Dement Geriatr Cogn Disord. 2018;46(1-2):109-118. doi: 10.1159/000492490. Epub 2018 Aug 24.


Background/aims: The aim of this study was to perform a psychometric validation of the Czech version of the Quality of Life - Alzheimer's Disease scale (QoL-AD) for patients with early-stage dementia.

Methods: The sample included 212 patient-proxy pairs. For convergent validity, the Czech version of the Bristol Activities of Daily Living Scale (BADLS-CZ), the Short Physical Performance Battery (SPPB), and the Geriatric Depression Scale (GDS) were used.

Results: The reliability of the QoL-AD for patients and caregivers was good (Cronbach's α = 0.85, ICC = 0.25-0.54). A positive correlation existed between the QoL-AD and the SPPB, and negative correlations existed between the QoL-AD and the BADLS-CZ as well as between the QoL-AD and the GDS. Factor analysis resulted in a three-factor solution (physical and mental health, family life, and social security).

Conclusion: The Czech version of the QoL-AD has good psychometric properties in compliance with international recommendations.

Keywords: Dementia; Geriatrics; Quality of life; Questionnaire.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Activities of Daily Living / psychology
  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / psychology*
  • Behavior Rating Scale / statistics & numerical data*
  • Czech Republic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psychometrics / statistics & numerical data*
  • Quality of Life / psychology*
  • Reproducibility of Results