Strategies for Antimicrobial Stewardship in Solid Organ Transplant Recipients

Infect Dis Clin North Am. 2018 Sep;32(3):535-550. doi: 10.1016/j.idc.2018.04.003.


Complications of antimicrobial therapy, such as multidrug-resistant organisms and Clostridium difficile, commonly affect solid-organ transplant recipients and have been associated with graft loss and mortality. Although opportunities are abundant, antimicrobial stewardship practices guiding appropriate therapy have been infrequently reported in transplant patients. A patient-centered, multidisciplinary structure, using established antimicrobial optimization principles, is needed to create nuanced approaches to protect patients and antimicrobials and improve outcomes.

Keywords: Antimicrobial stewardship; Immunocompromised hosts; Rapid diagnostics; Solid organ transplant.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Antimicrobial Stewardship*
  • Bacterial Infections / complications*
  • Bacterial Infections / prevention & control*
  • Humans
  • Organ Transplantation / adverse effects*
  • Postoperative Complications / prevention & control*


  • Anti-Bacterial Agents