Human Immunodeficiency Virus Organ Transplantation

Infect Dis Clin North Am. 2018 Sep;32(3):615-634. doi: 10.1016/j.idc.2018.04.013.

Abstract

Human immunodeficiency virus (HIV) has become a chronic disease with a near normal life span resulting in increased risk of organ failure. HIV organ transplantation is a proven and accepted intervention in appropriately selected cases. HIV-positive organ transplantation into HIV-positive recipients is in its nascent stages. Hepatitis C virus, high rates of organ rejection, and immune dysregulation are significant remaining barriers to overcome. This article provides an overview of the transplantation needs in the HIV population focusing on kidney and liver transplants.

Keywords: HIV; HIV positive to positive organ transplantation; Hepatitis C virus; Organ rejection; Organ transplantation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Graft Rejection
  • HIV Infections / complications*
  • Hepatitis C / transmission*
  • Hepatitis C / virology*
  • Humans
  • Organ Transplantation*
  • Tissue Donors
  • Transplant Recipients