Hemoptysis Originating from the Bronchial Artery in Takayasu Arteritis with Ulcerative Colitis

Intern Med. 2019 Jan 15;58(2):293-295. doi: 10.2169/internalmedicine.1463-18. Epub 2018 Aug 24.


Takayasu arteritis (TAK) is a large-vessel vasculitis affecting the aorta and its main branches. Hemoptysis can be experienced as the respiratory manifestation, but origination from a bronchial artery is rare. Ulcerative colitis (UC) shares genetic similarities with TAK; HLA-B52*01 is associated with TAK and UC. We herein report a patient who presented with hemoptysis from the right bronchial artery and was diagnosed with TAK during the follow-up of UC. Transcatheter embolization was performed, and prednisolone and tocilizumab induced remission. Complication of TAK should be considered in the clinical course of HLA-B52-positive UC patients, and tocilizumab may be a treatment option.

Keywords: Takayasu arteritis; bronchial arteries; hemoptysis; tocilizumab; ulcerative colitis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Bronchial Arteries*
  • Colitis, Ulcerative / complications*
  • Colitis, Ulcerative / genetics
  • Embolization, Therapeutic
  • HLA-B52 Antigen / genetics
  • Hemoptysis / etiology*
  • Hemoptysis / therapy
  • Humans
  • Male
  • Prednisolone / therapeutic use
  • Remission Induction
  • Takayasu Arteritis / complications*
  • Takayasu Arteritis / genetics
  • Young Adult


  • Anti-Inflammatory Agents
  • Antibodies, Monoclonal, Humanized
  • HLA-B52 Antigen
  • Prednisolone
  • tocilizumab