Presumed Tuberculous Sclerokeratitis Presenting with Hypopyon

Ocul Immunol Inflamm. 2019;27(7):1121-1123. doi: 10.1080/09273948.2018.1511812. Epub 2018 Aug 27.


Purpose: To describe a case of presumed tuberculous sclerokeratitis which presented with anterior uveitis and hypopyon Methods: A retrospective chart review Results: A 23-year-old female presented with nodular scleritis, peripheral corneal opacities, and severe anterior chamber reaction with hypopyon. Her Mantoux test and interferon gamma release assay were positive and high-resolution computerized tomography of chest revealed right hilar lymphadenopathy. Aqueous aspirate from anterior chamber paracentesis of her right eye was negative for Mycobacterium tuberculosis genome. She responded to antitubercular treatment and oral corticosteroid Conclusions: Tuberculous sclerokeratitis can rarely present with hypopyon and pose a challenge in diagnosis for the clinicians.

Keywords: Anti-tubercular treatment; hypopyon; interstitial keratitis; ocular tuberculosis; scleritis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Anterior Eye Segment / diagnostic imaging*
  • Antitubercular Agents / therapeutic use
  • Cornea / diagnostic imaging
  • Cornea / microbiology
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Keratitis / diagnosis*
  • Keratitis / microbiology
  • Mycobacterium tuberculosis / isolation & purification
  • Sclera / diagnostic imaging
  • Sclera / microbiology
  • Scleritis / diagnosis*
  • Scleritis / microbiology
  • Tuberculin Test
  • Tuberculosis, Ocular / diagnosis*
  • Tuberculosis, Ocular / microbiology
  • Visual Acuity*
  • Young Adult


  • Antitubercular Agents
  • Glucocorticoids