The use of avoidance training in studies of modulation of memory storage

Behav Neural Biol. 1986 Jul;46(1):87-98. doi: 10.1016/s0163-1047(86)90927-1.


Studies of the modulatory effects on memory of many treatments have relied in large part on the use of inhibitory (passive) avoidance training procedures. Recent critiques have questioned the validity of data obtained with the inhibitory avoidance task. This paper addresses these comments and describes many of the advantages of using the procedure in studies of processes which regulate the neurobiological mechanisms which store new information.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Arousal / drug effects
  • Avoidance Learning / physiology*
  • Biogenic Amines / physiology
  • Brain / physiology*
  • Conditioning, Classical / physiology
  • Male
  • Memory / drug effects
  • Memory / physiology*
  • Motivation / drug effects
  • Rats
  • Reaction Time
  • Synaptic Transmission
  • Vasopressins / physiology


  • Biogenic Amines
  • Vasopressins