Endovascular therapy of acute ischemic stroke related to tandem occlusion: comparison of occlusion and severe stenosis of the proximal cervical internal carotid artery

Br J Radiol. 2019 Jan;92(1093):20180051. doi: 10.1259/bjr.20180051. Epub 2018 Dec 3.

Abstract

Methods: We retrospectively reviewed 42 patients with acute ischemic stroke who underwent endovascular treatment for tandem lesions between January 2011 and April 2017. After dividing the patients into two groups according to lesion type of the proximal cervical ICA (complete occlusion and severe stenosis), we analyzed demographic data, angiographic findings and clinical outcomes. A modified Rankin Scale score ≤2 was defined as a favorable clinical outcome.

Results: Of 42 patients, 27 patients (64.3%) had complete occlusion of the cervical ICA, and the remaining 15 had high-grade stenosis. Successful stenting was performed in all patients with favorable clinical outcomes (27/42, 64.3%). Successful reperfusion score (thrombolysis in cerebral infarction ≥2b) was 78.6%; occlusion group (18/27, 66.7%) vs stenosis group (15/15, 100%) of cases. Mean modified Rankin Scale score at 90 days was 2.36 ± 1.83. The rate of favorable clinical outcome was higher in stenosis group (11/15, 73.3%) than that of occlusion group (16/27, 59.3%) with no statistically significant difference (p = 0.506).

Conclusion: Acute endovascular treatment of carotid artery tandem lesions is a technically feasible and clinically effective intervention regardless of the lesion type in proximal cervical ICA.

Advances in knowledge: Our study supports the results of previous studies in which endovascular therapy has a favorable clinical outcome in carotid artery tandem occlusion.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Brain Ischemia / diagnosis
  • Brain Ischemia / etiology
  • Brain Ischemia / therapy
  • Carotid Artery, Internal*
  • Carotid Stenosis / diagnostic imaging*
  • Carotid Stenosis / mortality
  • Carotid Stenosis / therapy*
  • Cohort Studies
  • Endovascular Procedures / methods*
  • Endovascular Procedures / mortality
  • Female
  • Follow-Up Studies
  • Hospital Mortality
  • Humans
  • Infarction, Middle Cerebral Artery / complications*
  • Infarction, Middle Cerebral Artery / diagnostic imaging
  • Magnetic Resonance Angiography / methods
  • Male
  • Middle Aged
  • Patient Safety*
  • Retrospective Studies
  • Risk Assessment
  • Stents
  • Stroke / diagnostic imaging
  • Stroke / etiology
  • Stroke / therapy
  • Treatment Outcome