Life Without Dreams: Muscarinic Receptors Are Required to Regulate REM Sleep in Mice
- PMID: 30157417
- DOI: 10.1016/j.celrep.2018.08.044
Life Without Dreams: Muscarinic Receptors Are Required to Regulate REM Sleep in Mice
Abstract
Mammalian sleep comprises REM and NREM stages, but the regulation mechanisms are unclear. In this issue of Cell Reports, Niwa et al. (2018) comprehensively knocked out cholinergic receptors in mice and found that muscarinic signaling is crucial for REM sleep and possibly important for NREM sleep.
Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.
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