Apical and basal-lateral Na/K-ATPase in rat lacrimal gland acinar cells
- PMID: 3015825
Apical and basal-lateral Na/K-ATPase in rat lacrimal gland acinar cells
Abstract
The distribution of Na/K-ATPase in rat exorbital lacrimal gland was studied using immunofluorescent localization of an antibody raised against rat kidney Na/K-ATPase. In cryostat sections, intralobular ducts were strongly immunoreactive and acinar cells showed localization on both apical and basal-lateral surfaces. Acinar cells also had strong intracellular reactivity in apical regions. These results are discussed in light of current models of exocrine gland electrolyte secretion.
Similar articles
-
Ultrastructural localization of Na+, K(+)-ATPase in the exorbital lacrimal gland of rat.Invest Ophthalmol Vis Sci. 1992 Jan;33(1):196-204. Invest Ophthalmol Vis Sci. 1992. PMID: 1309729
-
Surface and intracellular pools of Na,K-ATPase catalytic and immuno-activities in rat exorbital lacrimal gland.Exp Eye Res. 1993 Oct;57(4):403-13. doi: 10.1006/exer.1993.1141. Exp Eye Res. 1993. PMID: 8282026
-
Analytic subcellular fractionation of acini from rat lacrimal gland.Invest Ophthalmol Vis Sci. 1990 Nov;31(11):2437-47. Invest Ophthalmol Vis Sci. 1990. PMID: 2173690
-
Lacrimal fluid and electrolyte secretion: a review.Curr Eye Res. 1989 Jun;8(6):607-17. doi: 10.3109/02713688908995761. Curr Eye Res. 1989. PMID: 2545410 Review.
-
Subcellular organization of ion transporters in lacrimal acinar cells: secretagogue-induced dynamics.Adv Exp Med Biol. 1994;350:79-86. doi: 10.1007/978-1-4615-2417-5_14. Adv Exp Med Biol. 1994. PMID: 8030560 Review. No abstract available.
Cited by
-
Dry eye syndrome: comprehensive etiologies and recent clinical trials.Int Ophthalmol. 2022 Oct;42(10):3253-3272. doi: 10.1007/s10792-022-02320-7. Epub 2022 Jun 9. Int Ophthalmol. 2022. PMID: 35678897 Free PMC article. Review.
-
Expression of BK channels and Na+-K+ pumps in the apical membrane of lacrimal acinar cells suggests a new molecular mechanism for primary tear-secretion.Ocul Surf. 2019 Apr;17(2):272-277. doi: 10.1016/j.jtos.2019.01.007. Epub 2019 Jan 24. Ocul Surf. 2019. PMID: 30685438 Free PMC article.
-
Serotonin hormonally regulates lacrimal gland secretory function via the serotonin type 3a receptor.Sci Rep. 2017 Jul 31;7(1):6965. doi: 10.1038/s41598-017-06022-4. Sci Rep. 2017. PMID: 28761086 Free PMC article.
-
TFOS DEWS II pain and sensation report.Ocul Surf. 2017 Jul;15(3):404-437. doi: 10.1016/j.jtos.2017.05.002. Epub 2017 Jul 20. Ocul Surf. 2017. PMID: 28736339 Free PMC article. Review.
-
Age-related Defects in Ocular and Nasal Mucosal Immune System and the Immunopathology of Dry Eye Disease.Ocul Immunol Inflamm. 2016 Jun;24(3):327-47. doi: 10.3109/09273948.2014.986581. Epub 2014 Dec 23. Ocul Immunol Inflamm. 2016. PMID: 25535823 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
