Transit time flow measurement and high frequency ultrasound epicardial imaging to guide coronary artery bypass surgery

J Cardiovasc Surg (Torino). 2019 Apr;60(2):245-250. doi: 10.23736/S0021-9509.18.10549-0. Epub 2018 Aug 29.

Abstract

Background: Transit-time flow measurement (TTFM) should be routinely used in CABG surgery to verify graft function. Most recently, a 2D high-frequency-ultrasound (HF-US) epicardial imaging probe has been released (MiraQ™, Medistim, Oslo, Norway), which allows to evaluate the cannulation/clamping site of the aorta morphologically and to evaluate the completed anastomosis. We aimed to evaluate the use of TTFM and HF-US on surgical strategy during CABG surgery.

Methods: A total of 65 consecutive patients undergoing CABG surgery were evaluated. The target vessels, the clamping/cannulation site and the anastomosis were evaluated by HF-US. TTFM was performed on all grafts and the mean flow (mL/min) and pulsatility indices (PI) were recorded. Troponin-I levels (ng/L) were obtained within the first 4 postoperative days.

Results: A total of 3.3±0.9 grafts were performed, with 98.5% LIMA use and a sequential graft was performed in 55.4%. The mean PI and flow (mL/min) were 2.3±2.7 and 70.8±50.6 for the right coronary artery system, 2.4±2.2 and 82.0±47.6 for the circumflex system, and 2.1±1.2 and 78.0±35.0 for the LAD system, respectively. Postoperative troponin-I levels showed a maximum on postoperative day 1. A surgical strategy change, based on imaging, was done in 15%. Moreover, we observed a correlation of PI and flow with maximum postoperative troponin-I levels.

Conclusions: The present study evaluated the combination of TTFM and HF-US in CABG surgery. Epicardial scanning was helpful to evaluate the potential opening site of the vessel, to evaluate the completed anastomosis or to evaluate the clamping or cannulation site. Troponin-I levels were directly correlated to mean graft flow and PI levels.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Blood Flow Velocity
  • Coronary Artery Bypass / adverse effects
  • Coronary Artery Bypass / methods*
  • Coronary Circulation*
  • Coronary Vessels / diagnostic imaging*
  • Coronary Vessels / physiopathology
  • Coronary Vessels / surgery*
  • Echocardiography / methods*
  • Female
  • Humans
  • Intraoperative Care / methods*
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Pulsatile Flow
  • Pulse Wave Analysis
  • Time Factors
  • Treatment Outcome
  • Troponin I / blood
  • Vascular Patency

Substances

  • Biomarkers
  • Troponin I