Autoantibodies undetectable by chemiluminescent enzyme immunoassay require extended antigen-antibody reaction time for detection

Br J Dermatol. 2019 Jan;180(1):215-216. doi: 10.1111/bjd.17121. Epub 2018 Oct 10.

Authors

Y Mai¹, H Ujiie¹, T Higashi², J Yamagami³, H Iwata¹, H Shimizu¹

Affiliations

¹ Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita-ku, Sapporo, 060-8638, Japan.
² Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita-ku, Sapporo, 060-8638, Japan.
³ Department of Dermatology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

PMID: 30171687
DOI: 10.1111/bjd.17121

No abstract available

Publication types

Letter

MeSH terms

Adult
Aged
Antigen-Antibody Reactions*
Autoantibodies / blood*
Autoantibodies / immunology
Autoantigens / immunology
Desmoglein 1 / immunology
Desmoglein 3 / immunology
False Negative Reactions
Female
Humans
Immunoenzyme Techniques / methods*
Middle Aged
Pemphigus / blood
Pemphigus / diagnosis*
Pemphigus / immunology
Time Factors

Substances

Autoantibodies
Autoantigens
DSG1 protein, human
DSG3 protein, human
Desmoglein 1
Desmoglein 3