Adipose tissue, fillers, and skin tightening

Dermatol Ther. 2019 Mar;32(2):e12626. doi: 10.1111/dth.12626. Epub 2018 Sep 2.

Abstract

The role of adipose tissue has long been underestimated in esthetic dermatology. With the development of liposculpture and lipolysis, subcutaneous adipose tissue has gained an increasing interest. Harvested tissue has been used for lipofilling. In recent years, a better understanding of adipocyte physiology and its role in aging opened a new road for targeted treatments. Subcutaneous adipose tissue is no longer an innocent bystander in the combat of aging and the correction in esthetics. Adipose tissue is of importance for metabolic function and thermoregulation. Adipose tissue is involved in inflammation. Adipose tissue is heterogeneous in sense of function, color and size of adipocytes. The tissue is an important source of somatic stem cells.

Keywords: adipose tissue; adipose tissue-derived stem cells; body contouring; esthetic dermatology; lipofilling; lipolysis; liposculpture.

MeSH terms

  • Adipocytes / cytology
  • Adipose Tissue / transplantation
  • Cosmetic Techniques*
  • Humans
  • Lipolysis / physiology
  • Skin Aging*
  • Subcutaneous Fat / transplantation*